Article

SARS-CoV-2 diagnostic testing rates determine the sensitivity of genomic surveillance programs

2022-05-23

Abstract excerpt

The first step in SARS-CoV-2 genomic surveillance is testing to identify infected people. However, global testing rates are falling as we emerge from the acute health emergency and remain low in many low- and middle-income countries (LMICs) (mean = 27 tests/100,000 people/day). We simulated COVID-19 epidemics in a prototypical LMIC to investigate how testing rates, sampling strategies, and sequencing proportions j...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 19d2d065-c369-59d6-ab9f-3320f4e17aed
DOI: 10.1101/2022.05.20.22275319

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

SARS-CoV-2 diagnostic testing rates determine the sensitivity of genomic surveillance programsDOI 10.1101/2022.05.20.22275319Read

Low Testing Rates Limit the Ability of Genomic Surveillance Programs to Monitor SARS-CoV-2 Variants: A Mathematical Modelling StudySemantic proximity Read

Global disparities in SARS-CoV-2 genomic surveillanceSemantic proximity Read

Toward a COVID-19 testing policy: where and how to test when the purpose is to isolate silent spreadersSemantic proximity Read

Strategies for using antigen rapid diagnostic tests to reduce transmission of SARS-CoV-2 in low- and middle-income countries: a mathematical modelling study applied to ZambiaSemantic proximity Read

The analysis of a large dataset of PCR-test results in the community reveals the impact of age, variants and vaccination status on SARS-CoV-2 viral dynamicsSemantic proximity Read

Rapid incidence estimation from SARS-CoV-2 genomes reveals decreased case detection in Europe during summer 2020Semantic proximity Read

Rapid incidence estimation from SARS-CoV-2 genomes reveals decreased case detection in Europe during summer 2020Semantic proximity Read

SARS-CoV-2 Genome Sequencing Methods Differ In Their Ability To Detect Variants From Low Viral Load SamplesSemantic proximity Read

Leveraging Limited Testing Data for Early Detection of Emerging Infectious Disease OutbreaksSemantic proximity Read

Rapid incidence estimation from SARS-CoV-2 genomes reveals decreased case detection in Europe during summer 2020Semantic proximity Read

Tracking the prevalence and emergence of SARS-CoV-2 variants of concern using a regional genomic surveillance programSemantic proximity Read

Genomic surveillance at scale is required to detect newly emerging strains at an early timepointSemantic proximity Read