Article
Microbial determinants of dementia risk in subjects of Mexican descent with type 2 diabetes living in South Texas
2024-03-22
Abstract excerpt
Type 2 diabetes (T2D) is a common forerunner of neurodegeneration and dementia, including Alzheimer’s Disease (AD), yet the underlying mechanisms remain unresolved. Individuals of Mexican descent living in South Texas have increased prevalence of comorbid T2D and early onset AD, despite low incidence of the predisposing APOE-χ4 variant and an absence of the phenotype among relatives residing in Mexico – suggesting...
Topics
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- Alzheimer's disease research and treatments
- Clostridium difficile and Clostridium perfringens research
- Diet and metabolism studies
- Drug Transport and Resistance Mechanisms
- Gastrointestinal motility and disorders
- Gut microbiota and health
- Helicobacter pylori-related gastroenterology studies
- Tryptophan and brain disorders
Identifiers and source
- Literature Corpus work
- 832af273-abb3-5ed6-ab4a-3bac1a479cc8
- DOI
- 10.1101/2024.03.20.24304637
