Article

Cerebrospinal Fluid Proteomic Changes in Older Non-Cardiac Surgical Patients with Postoperative Cognitive Dysfunction

2020-06-18

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Postoperative cognitive dysfunction (POCD) is a syndrome of cognitive deficits that occurs in 10-40% of patients age > 60 within 1-12 months after surgery, hypothesized to be caused in part by neuroinflammation. However, the specific neuroinflammatory pathways involved remain unclear. Unbiased mass spectrometry-based proteomic analyses have been used to identify...

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Literature Corpus work: 82a644cf-51fc-5ce2-b9e8-41ec96df163d
DOI: 10.21203/rs.3.rs-35959/v1

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