Article

<i>MFN2</i> Influences Amyotrophic Lateral Sclerosis Pathology

2021-10-31

Abstract excerpt

<h4>Objective</h4> To better understand the pathology of amyotrophic lateral sclerosis, we used sequence data from patients seen at the University of Utah to identify novel disease-associated loci. We utilized both in vitro and in vivo studies to determine the biological effect of patient mutations in MFN2 . <h4>Method</h4> Sequence data for a total of 140 patients were run through VAAST and Phevor to determ...

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Literature Corpus work: 82944b64-33f3-51c9-8c34-d1d5103ec0d1
DOI: 10.1101/2021.10.30.466517

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