Article

Comparing Molecular Biomarker Testing With Immunohistochemical Staining In Predicting Response To Neoadjuvant Therapy In Breast Cancer

2022-03-02

Abstract excerpt

<h4>Background: </h4> Breast cancer (BC) is the most common cancer type among women world-wide and the major cause of cancer deaths. Many factors affect the prognosis and treatment of BC such as histological grading, staging, as well as the biological markers: Estrogen receptor (ER), Progesterone receptor (PR), HER2 and Ki67. Immunohistochemistry (IHC) remains the corner stone in determining ER, PR, HER2 and Ki67...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 826d4269-0538-5fcb-9bfd-fdb994932c15
DOI: 10.21203/rs.3.rs-1399752/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Comparing Molecular Biomarker Testing With Immunohistochemical Staining In Predicting Response To Neoadjuvant Therapy In Breast CancerDOI 10.21203/rs.3.rs-1399752/v1Read

Determination of Hormone Receptors, Human Epidermal Growth Factor Receptor 2 and Ki67 Status in Invasive Breast Carcinoma: A Concordance Study between Immunohistochemistry, Fluorescence in Situ Hybridization, and GeneXpert® Breast Cancer STRAT4 AssaySemantic proximity Read

Biomarker assessment and molecular testing for prognostication in breast cancerSemantic proximity Read

The Multi-Omic Transformation of Breast Cancer Diagnostics: A Comprehensive Review of the Transition from Immunohistochemistry to Liquid Biopsy and Next-Generation SequencingSemantic proximity Read

P53 immunohistochemistry is an ideal surrogate marker for TP53 mutation and a predictor of early metastasis in breast cancer: Real-world analysisSemantic proximity Read

[Clinically relevant molecular pathological diagnostics in breast cancer].Semantic proximity Read

Prognostic and predictive biomarkers with therapeutic targets in breast cancer: A 2022 update on current developments, evidence, and recommendationsSemantic proximity Read

The Changing Role of Pathology in Breast Cancer Diagnosis and TreatmentSemantic proximity Read

High concordance of 70-gene recurrence risk signature and 80-gene molecular subtyping signature between core needle biopsy and surgical resection specimens in early-stage breast cancerSemantic proximity Read

Comparative Analysis of Clinical and Molecular Characteristics in Invasive Ductal Carcinoma of the BreastSemantic proximity Read

Molecular characterization of breast cancer cell lines by clinical immunohistochemical markersSemantic proximity Read

Molecular intrinsic versus clinical subtyping in breast cancer: A comprehensive reviewSemantic proximity Read

American Society of Clinical Oncology/College of American Pathologists Guideline Recommendations for Human Epidermal Growth Factor Receptor 2 Testing in Breast CancerSemantic proximity Read