Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Modeling of Fabry disease nephropathy using patient derived human induced pluripotent stem cells and kidney organoid system

22 Feb 2023

Abstract excerpt

OBJECTIVES: To explore the possibility of kidney organoids generated using patient derived human induced pluripotent stem cells (hiPSC) for modeling of Fabry disease nephropathy (FDN). METHODS: First, we generated hiPSC line using peripheral blood mononuclear cells (PBMCs) from two male FD-patients with different types of GLA mutation: a classic type mutation (CMC-Fb-001) and a non-classic type (CMC-Fb-003)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Lysosomal Storage Disorders Research
Share to Pluripotent Stem Cells Research
Share to Renal and related cancers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36814269
DOI: 10.1186/s12967-023-03992-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Modeling of Fabry disease nephropathy using patient derived human induced pluripotent stem cells and kidney organoid systemPMID 36814269Read ↗

Modeling of Fabry disease nephropathy using patient derived human induced pluripotent stem cells and kidney organoid systemSemantic proximity Read ↗

CRISPR/Cas9-mediated A4GALT suppression rescues Fabry disease phenotypes in a kidney organoid model.Semantic proximity Read ↗

CRISPR-Cas9-Mediated Correction of SLC12A3 Gene Mutation Rescues the Gitelman's Disease Phenotype in a Patient-Derived Kidney Organoid System.Semantic proximity Read ↗

Human in vitro models for Fabry disease: new paths for unravelling disease mechanisms and therapies.Semantic proximity Read ↗

Advancements in Research on Genetic Kidney Diseases Using Human-Induced Pluripotent Stem Cell-Derived Kidney OrganoidsSemantic proximity Read ↗

Generation of human induced pluripotent stem cell line MHHi029-A from a male Fabry disease patient carrying c.959A > T mutation.Semantic proximity Read ↗

Human-induced pluripotent stem cell lines (CMCi006-A and CMCi007-A) from a female and male patient with Fabry disease carrying the same frameshift deletion mutation.Semantic proximity Read ↗

Towards Modelling Genetic Kidney Diseases with Human Pluripotent Stem Cells.Semantic proximity Read ↗

Human pluripotent stem cell-derived kidney organoids: Current progress and challengesSemantic proximity Read ↗

Combining Kidney Organoids and Genome Editing Technologies for a Better Understanding of Physiopathological Mechanisms of Renal Diseases: State of the ArtSemantic proximity Read ↗

Kidney Organoids as Disease Models: Strengths, Weaknesses and PerspectivesSemantic proximity Read ↗

3D organoid-derived human glomeruli for personalised podocyte disease modelling and drug screeningSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.