Article

Activation Ferroptosis Enhanced the Therapy Sensitivity of TNBC to Paclitaxel Via NCOA4 Mediated Ferritinophagy

2021-04-12

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>Paclitaxel (PTX) is the first-line drug for chemotherapy, but Triple-Negative Breast Cancer (TNBC) develops resistance to PTX is the main challenge in clinical therapy. Ferroptosis is a new type of regulated cell death (RCD) characterized by iron-dependent lipid peroxidation accumulation, despite activation of ferroptosis has been shown to enhance the sensibility...

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Literature Corpus work: 81c3e5f1-601c-5de1-bbf3-5674515ceb3b
DOI: 10.21203/rs.3.rs-360631/v1

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