Article

Single cell mapping of the human endometrium and first trimester decidua identifies distinct epithelial and stromal cell contributions to fertility

2025-04-26

Abstract excerpt

The human endometrium undergoes dynamic changes across the menstrual cycle to establish a receptive state for embryo implantation. Using bulk and single-cell RNA sequencing, we characterized gene expression dynamics in the cycling endometrium and the decidua from early pregnancy. We are the first to demonstrate that during the mid-secretory phase—the period encompassing the window of implantation—secretory glandul...

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Identifiers and source

Literature Corpus work: 813be490-ed23-5a72-9a29-07ae517e7b8e
DOI: 10.1101/2025.04.24.650488

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