Article

First-trimester exposure to anti-cytomegalovirus medications: a study of the effects of valaciclovir, letermovir and maribavir on early placental development

2025-05-07

Abstract excerpt

Congenital cytomegalovirus (CMV) infection is the leading preventable cause of childhood disability, including sensorineural hearing loss and cerebral palsy in high-income countries. Early maternal treatment with valaciclovir has been shown to reduce fetal infection. However, newer, more potent anti-CMV medications such as letermovir and maribavir are not routinely used in pregnancy due to limited safety data. Thi...

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Literature Corpus work: 810bcd72-c82b-5576-b6dd-ec31e7952f46
DOI: 10.1101/2025.05.01.651765

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