Article

In vivo Brain Estrogen Receptor Expression By Neuroendocrine Aging And Relationships With Gray Matter Volume, Bio-Energetics, and Clinical Symptomatology

2023-02-27

Abstract excerpt

<title>Abstract</title> <p>17β-estradiol,the most biologically active estrogen, exerts wide-ranging effects in brain through its action on estrogen receptors (ERs), influencing higher-order cognitive function and neurobiological aging. However, our knowledge of ER expression and regulation by neuroendocrine aging in the living human brain is limited. This <italic>in vivo</italic> multi-modality neuroimaging study...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 80f6fe3d-093d-5c93-bf2e-93cd93eb8cac
DOI: 10.21203/rs.3.rs-2573335/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

In vivo Brain Estrogen Receptor Expression By Neuroendocrine Aging And Relationships With Gray Matter Volume, Bio-Energetics, and Clinical SymptomatologyDOI 10.21203/rs.3.rs-2573335/v1Read

Menopause Impacts Human Brain Structure, Connectivity, Energy Metabolism, and Amyloid-beta Deposition.Semantic proximity Read

Postmortem tissue biomarkers of menopausal transitionSemantic proximity Read

Trajectories and phenotypes with estrogen exposures across the lifespan: What does Goldilocks have to do with it?Semantic proximity Read

Transitions in metabolic and immune systems from pre-menopause to post-menopause: implications for age-associated neurodegenerative diseasesSemantic proximity Read

Brain volumes in late life: gender, hormone treatment, and estrogen receptor variants.Semantic proximity Read

Estrogenic control of mitochondrial functionSemantic proximity Read

Estrogen receptor signaling and targets: Bones, breasts and brain (Review)Semantic proximity Read

Women’s brain aging: effects of sex-hormone exposure, pregnancies, and genetic risk for Alzheimer’s diseaseSemantic proximity Read

Relating sex differences in cortical and hippocampal microstructure to sex hormonesSemantic proximity Read

Perimenopause and emergence of an Alzheimer's bioenergetic phenotype in brain and periphery.Semantic proximity Read

Estradiol and memory circuitry in the postmenopause: Modification by APOE4Semantic proximity Read

Blood-based proteomic signatures of spontaneous menopause: Implications for later-life brain aging and Alzheimer’s disease riskSemantic proximity Read