Article

Schizophrenia, autism spectrum disorders and developmental disorders share specific disruptive coding mutations

2020-09-02

Abstract excerpt

Genes enriched for rare disruptive coding variants in schizophrenia overlap those in which disruptive mutations are associated with neurodevelopmental disorders (NDDs), particularly autism spectrum disorders and intellectual disability. However, it is unclear whether this implicates the same specific variants, or even variants with the same functional effects on shared risk genes. Here, we show that de novo mutat...

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Literature Corpus work: 8097d3a4-16a4-54ca-8cbd-9d307d2ea457
DOI: 10.1101/2020.09.02.279265

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