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Article

PARP inhibitor olaparib induces DNA damage and acts as a drug sensitizer in an in vitro model of canine hematopoietic cancer

2025-04-17

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> The introduction of genetic tests based on next-generation sequencing techniques into veterinary cancer diagnostics provides information on molecularly targeted therapies useful for dogs. However, there is still a lack of in vitro studies describing the effect and mechanism of action of such anticancer drugs in companion animals. Our study aimed to demonstrate in...

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Literature Corpus work
8034412c-d0b7-50d6-b034-4a9d76029de9
DOI
10.21203/rs.3.rs-6148132/v1
Open publication

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PARP inhibitor olaparib induces DNA damage and acts as a drug sensitizer in an in vitro model of canine hematopoietic cancerDOI 10.21203/rs.3.rs-6148132/v1
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