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Family With Sequence Similarity 46 Member A Confers Chemo-Resistance to Ovarian Carcinoma via TGF-β/Smad2 Signaling

2021-10-06

Abstract excerpt

<title>Abstract</title> <p><bold>Purpose: </bold>Ovarian cancer is the most lethal malignancy with depressive 5-year survival rate, mainly due to patients with advanced stages experience tumor recurrence and resistance to the current chemotherapeutic agents. Thus, discovering the underlying molecular mechanisms involved in chemo-resistance is crucial for management of treatment to improve therapeutic outcomes. <b...

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Literature Corpus work
80255626-336b-5366-a6b5-6759bf21ea8b
DOI
10.21203/rs.3.rs-951414/v1
Open publication

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