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Article

MYCN RNA levels determined by quantitative in situ hybridization is better than MYCN gene dosages in predicting the prognosis of neuroblastoma patients.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Apr 2020

Chang Hsiu-Hao, Tseng Yu-Fen, Lu Meng-Yao, Yang Yung-Li, Chou Shu-Wei, Lin Dong-Tsamn, Lin Kai-Hsin, Jou Shiann-Tarng, Hsu Wen-Ming, Jeng Yung-Ming

Abstract excerpt

The aim of this study was to investigate the prognostic role of MYCN RNA expression by quantitative RNA in situ hybridization and its association with MYCN amplification in neuroblastoma. MYCN RNA expression in 69 neuroblastoma tumors was evaluated by an ultrasensitive quantitative RNA in situ hybridization technique, RNAscope. The correlations between MYCN RNA expression, MYCN amplification, and other...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31695155
DOI: 10.1038/s41379-019-0410-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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