Article

NSF mediates CDC5L nuclear import to promote cell growth and metastasis in hepatocellular carcinoma

2023-03-20

Abstract excerpt

<title>Abstract</title> <p>Intracellular transportation (IT) is dysregulated in tumors. Here, we identified <italic>N</italic>-ethylmaleimide-sensitive factor (NSF) as one of the IT-associated genes with upregulated expression in hepatocellular carcinoma (HCC). Furthermore, NSF expression is associated with malignant features and poor outcomes of HCC patients. NSF acts as an oncogenic driver that promotes HCC cel...

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Literature Corpus work: 7fae167a-459a-5f0b-926f-4d6cbaa1d220
DOI: 10.21203/rs.3.rs-2608617/v1

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