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Article

Increased expression of Cyclin F in liver cancer predicts poor prognosis: A study based on TCGA database.

Medicine - 6 Aug 2021

Zelong Yang, Han Yang, Ting Guo, Yifei Wang, Kun He, Haoran Hu, Yong Chen

Abstract excerpt

BACKGROUND: Cyclin F (CCNF) dysfunction has been implicated in various forms of cancer, offering a new avenue for understanding the pathogenic mechanisms underlying hepatocellular carcinoma (HCC). We aimed to evaluate the role of CCNF in HCC using publicly available data from The Cancer Genome Atlas (TCGA). METHOD: We used TCGA data and Gene Expression Omnibus (GEO) data to analyze the differential expression of...

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PMID: 34397798
DOI: 10.1097/MD.0000000000026623
PMCID: PMC8341327

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