Article

Macrophages inhibit and enhance endometriosis depending on their origin

2020-05-02

Abstract excerpt

Macrophages are intimately involved in the pathophysiology of endometriosis, a chronic inflammatory disorder characterized by the growth of endometrial-like tissue (lesions) outside the uterus. By combining genetic and pharmacological monocyte and macrophage depletion strategies we determined the ontogeny and function of macrophages in a mouse model of induced endometriosis. We demonstrate that lesion-resident mac...

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Literature Corpus work: 7f22b47e-9173-50f3-8456-53cc2ce89117
DOI: 10.1101/2020.04.30.070003

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