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Article

Single-cell analysis identifies distinct macrophage phenotypes associated with prodisease and proresolving functions in the endometriotic niche.

Proceedings of the National Academy of Sciences of the United States of America - 17 Sept 2024

Henlon Yasmin, Panir Kavita, McIntyre Iona, Hogg Chloe, Dhami Priya, Cuff Antonia O, Senior Anna, Moolchandani-Adwani Niky, Courtois Elise T, Horne Andrew W, Rosser Matthew, Ott Sascha, Greaves Erin

Abstract excerpt

Endometriosis negatively impacts the health-related quality of life of 190 million women worldwide. Novel advances in nonhormonal treatments for this debilitating condition are desperately needed. Macrophages play a vital role in the pathophysiology of endometriosis and represent a promising therapeutic target. In the current study, we revealed the full transcriptomic complexity of endometriosis-associated...

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Disease Models, Animal
Endometriosis
Endometrium
Human Umbilical Vein Endothelial Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Single-Cell Analysis

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PMID: 39255000
DOI: 10.1073/pnas.2405474121
PMCID: PMC11420174

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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