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Flotillin-1 as a housekeeping target mediates Nrf2 inhibition of blood–retinal barrier ferroptosis in diabetic retinopathy

2023-10-19

Abstract excerpt

Disruption of the blood-retinal barrier causes the development of diabetic retinopathy (DR). The mechanism of damage to retinal pigment epithelial (RPE) cells, retinal microvascular endothelial cells, and related targets is still awaiting in depth studies. In this study, flotillin-1, a key protein downregulated during the progression of DR, was screened by basic bioinformatics and was found to positively regulate...

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Literature Corpus work
7ef43ff7-34ac-59f0-abfb-145c0c1dc477
DOI
10.21203/rs.3.rs-3450927/v1
Open publication

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Flotillin-1 as a housekeeping target mediates Nrf2 inhibition of blood–retinal barrier ferroptosis in diabetic retinopathyDOI 10.21203/rs.3.rs-3450927/v1
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