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Molecular Mechanisms of Iron Mediated Programmed Cell Death and Its Roles in Eye Diseases

5 Apr 2022

Abstract excerpt

Ferroptosis, a newly identified, iron-dependent type of programmed cell death, is active in several diseases, such as heart disease, brain damage, and cancer. Its main characteristics commonly involve excess iron accumulation, elevated lipid peroxides and reactive oxygen species, and reduced levels of glutathione and glutathione peroxidase 4 levels. The effects of ferroptosis in eye diseases cannot be...

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PMID: 35495915
DOI: 10.3389/fnut.2022.844757

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