Back to search

Article

Transcriptomic signature of Human Cardiac Fibroblast in Hypertrophic Obstructive Cardiomyopathy

2026-07-17

Abstract excerpt

<h4>Background</h4> Hypertrophic Cardiomyopathy (HCM) is a cardiac disorder characterized by an increased interstitial fibrosis and Extracellular Matrix (ECM) remodeling. Cardiac fibroblasts (CFs) have a crucial role in ECM remodeling as well as influencing contractility. There is accumulating evidence that the phenotype of CFs is disease-specific. Here, we investigate the transcriptome signature of CFs in Hypert...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
7e843b84-a92e-5412-9fe2-b3b1f0380d7c
DOI
10.64898/2026.07.12.738095
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Transcriptomic signature of Human Cardiac Fibroblast in Hypertrophic Obstructive CardiomyopathyDOI 10.64898/2026.07.12.738095
Integrative Single-Cell Analysis of Cardiomyopathy Identifies Differences in Cell Stemness and Transcriptional Regulatory Networks among Fibroblast SubpopulationsSemantic proximity
Integration mapping of cardiac fibroblast single-cell transcriptomes elucidates cellular principles of fibrosis in diverse pathologiesSemantic proximity
Unveiling Immune Infiltration Characterizing Genes in Hypertrophic Cardiomyopathy Through Transcriptomics and BioinformaticsSemantic proximity
High‐resolution single‐cell transcriptomic survey of cardiomyocytes from patients with hypertrophic cardiomyopathySemantic proximity
Characterising Shared and Specific Cell–Cell Communication in Cardiomyopathy Subtypes From Single‐Cell Transcriptomics DataSemantic proximity
Immune Transcriptional Signatures Across Human Cardiomyopathy Subtypes: A Multi-Cohort Integrative Computational AnalysisSemantic proximity
An 'Omics' Perspective on Cardiomyopathies and Heart Failure.Semantic proximity
Proteomic Characterisation of Heart Failure Reveals a Unique Molecular Phenotype for Hypertrophic CardiomyopathySemantic proximity
Lineage-specific regulatory changes in the pathological cardiac remodeling of hypertrophy cardiomyopathy unraveled by single-nucleus RNA-seq and spatial transcriptomicsSemantic proximity
Cardiac Fibrosis in the Multi-Omics Era: Implications for Heart FailureSemantic proximity
Transcriptome and proteome profiling of activated cardiac fibroblasts supports target prioritization in cardiac fibrosisSemantic proximity
Integration of dilated cardiomyopathy genomics with transcriptomics from the human heart implicates regulatory molecular mechanismsSemantic proximity
Select a neighboring publication to make it the new centre.