Article

A gavage-fomite based method to generate mouse models with natural microbiota

2026-06-19

Abstract excerpt

Laboratory-raised specific pathogen-free (SPF) mice have been indispensable for fundamental immunology research, yet their reliability in predicting human clinical outcomes has been questionable. A major factor contributing to this disconnect is the sanitized housing environment, which deprives laboratory mice of physiological microbial exposure critical for immune maturation. Various approaches have been develope...

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Literature Corpus work: 7e7db02f-3164-5cd0-8ade-09a3845996f0
DOI: 10.64898/2026.06.15.732393

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