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The antifungal activity of o-vanillin against Aspergillus flavus via disrupting ergosterol biosynthesis and promoting oxidative stress, and an RNA-seq analysis thereof

2022-07-01

Abstract excerpt

o-Vanillin is an effective plant-derived compound inhibiting the growth of Aspergillus flavus (A. flavus). In this study, o-vanillin disrupted the cell membrane of A. flavus via hindering K⁺ transport across plasma membrane, decreasing the content of lipid, ergosterol and trehalose, and inducing lipid peroxidation. The HOG pathway might be upregulated as the content of glycerol increased. Moreover, o-vanillin sign...

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Literature Corpus work
7e5a6cc1-ef63-5419-aa2d-a75ed800d196
DOI
10.1016/j.lwt.2022.113635
Open publication

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The antifungal activity of o-vanillin against Aspergillus flavus via disrupting ergosterol biosynthesis and promoting oxidative stress, and an RNA-seq analysis thereofDOI 10.1016/j.lwt.2022.113635
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