Article

Selectomic and Evolvability Analyses of the Highly Pathogenic Betacoronaviruses SARS-CoV-2, SARS-CoV, and MERS-CoV

2020-05-05

Abstract excerpt

SARS-CoV-2, the causative agent of COVID-19, is widespread in several countries around the world following its late-2019 emergence in the human population. Rapid development of molecular diagnostic tests and subunit vaccines have been prioritized, and as such evaluating the SARS-CoV-2 genomic plasticity and evolutionary dynamics is an urgent need. We determined the SARS-CoV-2 selectome by calculating rates of perv...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7e49ebf1-d434-5470-b0df-e3692b61259b
DOI: 10.1101/2020.05.05.078956

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Selectomic and Evolvability Analyses of the Highly Pathogenic Betacoronaviruses SARS-CoV-2, SARS-CoV, and MERS-CoVDOI 10.1101/2020.05.05.078956Read

Ongoing natural selection drives the evolution of SARS-CoV-2 genomesSemantic proximity Read

Evolutionary trajectory of SARS-CoV-2 genome shifts during widespread vaccination and emergence of Omicron variantSemantic proximity Read

Ongoing Positive Selection Drives the Evolution of SARS-CoV-2 GenomesSemantic proximity Read

Genome-Wide Variation in Betacoronaviruses.Semantic proximity Read

Genomic Analysis of SARS-CoV-2 Alpha, Beta and Delta Variants of Concern Uncovers Signatures of Neutral and Non-Neutral Evolution.Semantic proximity Read

Heterogeneous Evolution Among SARS‐CoV‐2 Genes and Variants of ConcernSemantic proximity Read

Ongoing global and regional adaptive evolution of SARS-CoV-2.Semantic proximity Read

Positive Selection of ORF1ab, ORF3a, and ORF8 Genes Drives the Early Evolutionary Trends of SARS-CoV-2 During the 2020 COVID-19 PandemicSemantic proximity Read

Genomic-epidemiological analysis of 15 million SARS-CoV-2 genomes reveals accelerated fitness gain of JN.1 lineage.Semantic proximity Read

Positive selection of ORF3a and ORF8 genes drives the evolution of SARS-CoV-2 during the 2020 COVID-19 pandemicSemantic proximity Read

On the evolutionary epidemiology of SARS-CoV-2.Semantic proximity Read

Predicting the past and future evolutionary space of SARS-CoV-2Semantic proximity Read