Article

Integrative transcriptomic analysis identifies miR-642a-5p as a regulator of <i>POFUT1</i> expression in colon cancer

2025-11-05

Abstract excerpt

<h4>Background</h4> Colorectal cancer (CRC) is one of the most common and deadly cancers worldwide, underscoring the urgent need for novel biomarkers and therapeutic targets. Protein O -fucosyltransferase 1 (POFUT1) is increasingly recognized as an oncogenic driver in CRC, but the upstream regulatory mechanisms responsible for its overexpression remain poorly understood. <h4>Objective</h4> We aimed to identify...

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Literature Corpus work: 7cfd0eda-c9f1-5acf-a28d-f0c81c30088a
DOI: 10.1101/2025.11.03.686298

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