Article

Increased Histone-DNA Complexes and Endothelial-Dependent Thrombin Generation in Severe COVID-19

2021-07-05

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> Coagulopathy in severe COVID-19 is common but poorly understood. The purpose of this study was to determine how SARS-CoV-2 infection impacts histone levels, fibrin structure, and endogenous thrombin potential in the presence and absence of endothelial cells. <h4>Approach</h4> We studied individuals with SARS-CoV-2 infection and acute respiratory distress syndrome at the time...

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Literature Corpus work: 7c8eee6f-ab6d-52f6-8fd5-f500ab6933ef
DOI: 10.1101/2021.07.03.450992

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