Article

Single-cell analysis of the somatic mutational landscape in human chondrocytes during aging and in osteoarthritis

2024-08-25

Abstract excerpt

Somatic mutation is now recognized as a cause of multiple human diseases other than cancer. Osteoarthritis (OA), a highly prevalent age-related disease, has been associated with increased chromosomal abnormalities in articular cartilage of OA patients. Thus far no systematic attempt has been made to characterize the somatic mutational landscape of chondrocytes during normal aging and in affected cartilage of OA pa...

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Literature Corpus work: 7c8e1f89-48c9-5ddf-8c00-6ce729c58746
DOI: 10.1101/2024.08.24.609506

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