Article

Tendency towards being a “Morning person” increases risk of Parkinson’s disease: evidence from Mendelian randomisation

2018-03-26

Abstract excerpt

<h4>Background</h4> Circadian rhythm may play a role in neurodegenerative diseases such as Parkinson’s disease (PD). Chronotype is the behavioural manifestation of circadian rhythm and Mendelian randomisation (MR) involves the use of genetic variants to explore causal effects of exposures on outcomes. This study aimed to explore a causal relationship between chronotype and coffee consumption on risk of PD. <h4>Me...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7c2985ed-efab-53a8-9e4f-afad5e309fa9
DOI: 10.1101/288241

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Tendency towards being a “Morning person” increases risk of Parkinson’s disease: evidence from Mendelian randomisationDOI 10.1101/288241Read

Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythmsSemantic proximity Read

Coffee consumption is associated with later age-at-onset of Parkinson’s diseaseSemantic proximity Read

Genome-wide association analyses of chronotype in 697,828 individuals provides new insights into circadian rhythms in humans and links to diseaseSemantic proximity Read

Investigating the Genetic Association of 40 Biochemical Indicators with Parkinson's Disease.Semantic proximity Read

GWAS of 89,283 individuals identifies genetic variants associated with self-reporting of being a morning person.Semantic proximity Read

Morning chronotype and digestive tract cancers: Mendelian randomization study.Semantic proximity Read

Exploring the causal association between 6 sleep traits and Parkinson disease.Semantic proximity Read

Genetically proxied morning chronotype was associated with a reduced risk of prostate cancer.Semantic proximity Read

<scp>M</scp> endelian <scp>R</scp> andomization — the <scp>K</scp> ey to <scp>U</scp> nderstanding <scp>A</scp> spects of <scp>P</scp> arkinson's <scp>D</scp> isease <scp>C</scp> ausation?Semantic proximity Read

Bidirectional Mendelian randomization to explore the causal relationships between Sleep traits, Parkinson's disease and Amyotrophic lateral sclerosis.Semantic proximity Read

Physical activity and Parkinson’s disease: a two-sample Mendelian randomisation studySemantic proximity Read

Do sex hormones confound or mediate the effect of chronotype on breast and prostate cancer? A Mendelian randomization studySemantic proximity Read