Article

ASPECT: Alternative Splicing Event Classification with Transformers

2026-02-06

Abstract excerpt

<h4>Motivation</h4> Alternative splicing (AS) is a fundamental regulatory mechanism that expands transcriptomic and proteomic diversity by generating multiple mRNA isoforms from a single gene. Aberrant AS has been implicated in numerous diseases through the production of dysfunctional or pathogenic protein variants. However, much of the existing AS research has focused predominantly on exon skipping and constitut...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7bd1c16b-2386-53cc-86dc-64cef255d2a9
DOI: 10.64898/2026.02.04.700904

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

ASPECT: Alternative Splicing Event Classification with TransformersDOI 10.64898/2026.02.04.700904Read

Detection of alternative splicing: deep sequencing or deep learning?Semantic proximity Read

Aberrant splicing prediction across human tissuesSemantic proximity Read

SpliceDecoder: A High-Throughput Tool for Guiding the Functional Interpretation of Differential Splicing EventsSemantic proximity Read

Improving splice site usage prediction with SPLAIRESemantic proximity Read

Pathogenicity prediction for noncanonical splice-altering variants based on multimodal feature fusion.Semantic proximity Read

Analyzing the Performance of Deep Learning Splice Prediction AlgorithmsSemantic proximity Read

ExonImpact: Prioritizing Pathogenic Alternative Splicing Events.Semantic proximity Read

Perturbation-aware predictive modeling of RNA splicing using bidirectional transformersSemantic proximity Read

Introducing STRAND: A Foundational Sequence Transformer for Range Adaptive Nucleotide DecodingSemantic proximity Read

Alternative splicing analysis benchmark with DICASTSemantic proximity Read

Introme accurately predicts the impact of coding and noncoding variants on gene splicing, with clinical applications.Semantic proximity Read

Reference-informed prediction of alternative splicing and splicing-altering mutations from sequencesSemantic proximity Read