Article

Fast pairwise coalescence enables gene-resolution scans for recent selection in diverse human populations

2026-05-22

Abstract excerpt

Identifying the genetic changes that shaped recent human adaptation depends on our ability to detect selection from genomic data. Summary statistics from haplotype scans have been widely used for that purpose, aggregating genetic signal over windows, though resolution is limited by linkage and their power may diminish as sweeps approach fixation, as in the case of the integrated haplotype score (iHS). Ancient DNA...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7bc617e7-35a6-565e-b70f-ae90dd2256ac
DOI: 10.64898/2026.05.21.726777

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Fast pairwise coalescence enables gene-resolution scans for recent selection in diverse human populationsDOI 10.64898/2026.05.21.726777Read

Pervasive findings of directional selection realize the promise of ancient DNA to elucidate human adaptationSemantic proximity Read

Genome-wide genealogies reveal deep admixtures forming modern humansSemantic proximity Read

High-throughput inference of pairwise coalescence times identifies signals of selection and enriched disease heritability.Semantic proximity Read

Information compression exploits patterns of genome composition to discriminate populations and highlight regions of evolutionary interest.Semantic proximity Read

Human genome sequence variation and the influence of gene history, mutation and recombination.Semantic proximity Read

Inferring population histories for ancient genomes using genome-wide genealogiesSemantic proximity Read

A method for genome-wide genealogy estimation for thousands of samplesSemantic proximity Read

Models of archaic admixture and recent history from two-locus statisticsSemantic proximity Read

Reconstructing the history of founder events using genome-wide patterns of allele sharing across individualsSemantic proximity Read

Tracking human population structure through time from whole genome sequencesSemantic proximity Read

Identity-by-descent detection across 487,409 British samples reveals fine scale population structure and ultra-rare variant associations.Semantic proximity Read

Identifying and classifying shared selective sweeps from multilocus dataSemantic proximity Read