Article

DPP6 gene in European American Alzheimer’s Disease

2020-10-27

Abstract excerpt

DPP6 encodes a transmembrane protein that expresses highly in the hippocampal regions of the brain and regulates dendritic excitability. Recently, rare and loss of function variants were reported in DPP6 and further demonstrated to be associated with early onset Alzheimer Disease (AD) and frontotemporal dementia. We performed single variant and gene-based analyses in three non-Hispanic white cohorts: a familial la...

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Literature Corpus work: 7ad3edf7-0cf1-51d1-951e-933143751b94
DOI: 10.1101/2020.10.23.20216408

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