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System-level analysis of genes mutated in muscular dystrophies reveals a functional pattern associated with muscle weakness distribution

2024-01-07

Abstract excerpt

<h4>ABSTRACT</h4> Muscular dystrophies (MDs) are inherited genetic diseases causing weakness and degeneration of muscles. The distribution of muscle weakness differs between MDs, involving distal muscles or proximal muscles. While the mutations in most of the MD-associated genes lead to either distal or proximal onset, there are also genes whose mutations can cause both types of onsets. We hypothesized that the g...

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Literature Corpus work
7aaa6400-ef74-5a97-b4d5-b7edba2b6ccb
DOI
10.1101/2024.01.05.574331
Open publication

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System-level analysis of genes mutated in muscular dystrophies reveals a functional pattern associated with muscle weakness distributionDOI 10.1101/2024.01.05.574331
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