Article

PKM2 promotes lymphatic metastasis of hypopharyngeal carcinoma via regulating Epithelial-Mesenchymal Transition

2023-02-08

Abstract excerpt

<h4>Objective: </h4> Patients with hypopharyngeal carcinoma (HPC) have a poor prognosis mainly because of lymphatic metastasis (LM). This research aimed to determine the PKM2 role in LM in HPC and the underlying molecular mechanism contributing to this phenomenon. Methods PKM2 in HPC was studied for its expression and its likelihood of overall survival using TCGA dataset. Kaplan-Meier and COX's regression analysis...

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Literature Corpus work: 7a265700-5a7f-536a-b837-bcc37cf551b4
DOI: 10.21203/rs.3.rs-2555690/v1

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