Article

Super-Resolved Single Small Extracellular Vesicle Assay enabled by a Plasmonic Nanohole Array

2026-06-16

Abstract excerpt

The accurate quantification of biological nanoparticles, such as small extracellular vesicles (sEVs), is fundamentally hindered by a resolution-coincidence trade-off in digital assays. While physical confinement can isolate single particles, conventional optical readouts remain diffraction-limited, causing multi-particle occupancy to be miscounted as single events and thereby restricting the analytical dynamic ran...

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Literature Corpus work: 78fc41c5-2dc6-5deb-b644-4e2cdc943f37
DOI: 10.64898/2026.06.12.731868

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