Article

Agent-based modeling of DFNB1A prevalence with regard to intensity of selection pressure in isolated human population: will cochlear implantation increase the cases of hereditary deafness?

2021-08-13

Abstract excerpt

<h4>ABSTRACT</h4> It was evidenced, that the increase in the prevalence of autosomal recessive deafness 1A (DFNB1A) in populations of European descent was promoted by assortative marriages among deaf people. Assortative marriages become possible with a widespread introduction of sign language resulting in increased the genetic fitness of deaf individuals, thus relaxing selection against deafness. Currently, cochle...

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Literature Corpus work: 78d15c2b-0278-5bab-9637-08b27a75bc6e
DOI: 10.1101/2021.08.11.21261942

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