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In vitro demonstration of broad host range mobile genetic elements transferring antibiotic resistance from the human microbiome

2022-01-18

Abstract excerpt

Mobile genetic elements (MGEs) carrying antibiotic resistance genes (ARGs) disseminate ARGs when they mobilise into new bacterial hosts. To investigate the scale of such horizontal gene transfer (HGT) events between human gut commensals and enteropathogens for the first time, we compared 1354 cultured commensal strains (540 species) to 45,403 enteropathogen strains (12 species) and found 64,188 MGE-mediated ARG tr...

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Literature Corpus work
89d6c137-9964-5d73-8fac-74efee0d6daa
DOI
10.1101/2022.01.18.476738
Open publication

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In vitro demonstration of broad host range mobile genetic elements transferring antibiotic resistance from the human microbiomeDOI 10.1101/2022.01.18.476738
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