Article

The gut microbiota and colonic pH map to the peripheral immune landscape in humans

2025-12-04

Abstract excerpt

<h4>Background</h4> The regional physicochemical environment of the gut, particularly colonic pH, is a key determinant of microbial composition and metabolic activity. However, how these localised intraluminal physicochemical dynamics interface with systemic immunity in humans remains unknown. <h4>Objective</h4> We aimed to investigate the relationship between colonic pH, microbial metabolism, and immune tone. <...

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Literature Corpus work: 787981fd-d0ff-5d6e-a316-da7713fc7972
DOI: 10.64898/2025.12.02.25341510

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