Article

Blood drops to gut maps: dried blood spot metabolomics infers gut microbiome composition and guides probiotic intervention in metabolic disease

2026-05-18

Abstract excerpt

<title>Abstract</title> <p>Blood metabolomics could offer a minimally invasive route to monitor gut microbiome–host interactions in metabolic disease, but existing serum or plasma approaches are logistically demanding and rarely evaluated in interventional settings. Here we develop and clinically test the Gut Function Test (GFT), a dried blood spot–based LC–MS and elastic-net framework that predicts genus-level g...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2344959c-9a43-5a2b-a4a0-796deaf3f7df
DOI: 10.21203/rs.3.rs-9134629/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Blood drops to gut maps: dried blood spot metabolomics infers gut microbiome composition and guides probiotic intervention in metabolic diseaseDOI 10.21203/rs.3.rs-9134629/v1Read

Predicting diabetic kidney disease with serum metabolomics and gut microbiotaSemantic proximity Read

Integration of gut microbiome, host biomarkers, and urine metabolome data reveals networks of interactions associated with distinct clinical phenotypesSemantic proximity Read

The Gut Microbiota and Diabetes: Research, Translation, and Clinical Applications—2023 Diabetes , Diabetes Care , and Diabetologia Expert ForumSemantic proximity Read

The Gut Microbiota and Diabetes: Research, Translation, and Clinical Applications—2023 Diabetes, Diabetes Care, and Diabetologia Expert ForumSemantic proximity Read

Integrated multi-omics analysis reveals the functional signature of microbes and metabolomics in pre-diabetes individualsSemantic proximity Read

Population-scale Characterization of the Oral Microbiome and Associations with Metabolic HealthSemantic proximity Read

An online atlas of human plasma metabolite signatures of gut microbiome compositionSemantic proximity Read

Blood metabolomic shift links diet and gut microbiota to multiple health outcomes among Hispanic/Latino immigrants in the U.S.Semantic proximity Read

Population-scale characterization of the oral microbiome and associations with metabolic health.Semantic proximity Read

Data-driven precision nutrition improves clinical outcomes and risk scores for IBS, depression, anxiety, and T2DSemantic proximity Read

Systems Biology of Human Microbiome for the Prediction of Personal Glycaemic ResponseSemantic proximity Read

Far from the gut but still relevant? Circulating bacterial signature is linked to metabolic disease and shifts with metabolic alleviation after bariatric surgerySemantic proximity Read