Article

Contribution of uniparental disomy to fetal growth restriction: a whole-exome sequencing series in a prenatal setting

2023-09-29

Abstract excerpt

Fetal growth restriction (FGR), a leading cause of perinatal morbidity and mortality, is caused by fetal, maternal, and placental factors. Uniparental disomy (UPD) is a rare condition that leads to imprinting effects, low-level mosaic aneuploidies and homozygosity for pathogenic variants. In the present study, UPD events were detected in 5 women with FGR by trio exome sequencing (trio-WES) of a cohort of 150 FGR c...

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Literature Corpus work: 784ed1b8-c522-5edb-9cb5-9f7a39660381
DOI: 10.21203/rs.3.rs-3347215/v1

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