Back to search

Article

Predictive model for BNT162b2 vaccine response in cancer patients based on cytokines and growth factors

2022-09-27

Abstract excerpt

<h4>A bstract </h4> <h4>Background</h4> Patients with cancer, especially haematological cancer, are at increased risk for breakthrough COVID-19 infection. However, so far, a predictive biomarker that can assess compromised vaccine-induced anti-SARS-CoV-2 immunity in cancer patients has not been proposed. <h4>Methods</h4> Here, we employed machine learning approaches to identify a biomarker signature based on blood...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
779ad1c3-9675-5481-9000-56d800cd5740
DOI
10.1101/2022.09.25.22280267
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Predictive model for BNT162b2 vaccine response in cancer patients based on cytokines and growth factorsDOI 10.1101/2022.09.25.22280267
MicroRNAs immune response profile to COVID-19 vaccine boost in cancer patients under active treatmentSemantic proximity
Identifying baseline immune-related biomarkers to predict clinical outcome of immunotherapy.Semantic proximity
Interim results of the safety and immune-efficacy of 1 versus 2 doses of COVID-19 vaccine BNT162b2 for cancer patients in the context of the UK vaccine priority guidelinesSemantic proximity
Systems biology analysis reveals distinct molecular signatures associated with immune responsiveness to the BNT162b COVID-19 vaccineSemantic proximity
Construction and evaluation of clinical prediction model for immunotherapy-related adverse events and clinical benefit in cancer patients receiving immune checkpoint inhibitors based on serum cytokine levelsSemantic proximity
Cytokine profile of anti-spike CD4+T cells predicts humoral and CD8+T cell responses after anti-SARS-CoV-2 mRNA vaccinationSemantic proximity
Systemic IL-15, IFN-γ and IP-10/CXCL10 Signature Associated With Effective Immune Response in BNT162b2 mRNA Vaccine RecipientsSemantic proximity
Dysregulated inflammation in solid tumor malignancy patients shapes polyfunctional antibody responses to COVID-19 vaccinationSemantic proximity
COVID-19–Sensitive Tumour Response – 2-Year Assessment of the SARS-CoV-2 Humoral Response in Cancer Patients in Oncology Hospital in PolandSemantic proximity
TMB: a promising immune-response biomarker, and potential spearhead in advancing targeted therapy trialsSemantic proximity
Unlocking the Potential of Therapy-Induced Cytokine Responses: Illuminating New Pathways in Cancer Precision MedicineSemantic proximity
Cytokine Storms in Cancer and COVID-19Semantic proximity
Select a neighboring publication to make it the new centre.