Article
Discovery of paralogous GnRH and corazonin signaling systems in an invertebrate chordate
2023-03-07
Abstract excerpt
Gonadotropin-releasing hormone (GnRH) is a key regulator of reproductive function in vertebrates. GnRH is related to the corazonin (CRZ) neuropeptide which influences metabolism and stress responses in insects. Recent evidence suggests that GnRH and CRZ are paralogous and arose by a gene duplication in a common ancestor of bilaterians. Here we report the identification and complete characterization of the GnRH and...
Topics
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- Amino Acid Sequence
- Conserved Sequence
- Evolution, Molecular
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Hypothalamic control of reproductive hormones
- Neurobiology and Insect Physiology Research
- Ovarian function and disorders
- Reproductive biology and impacts on aquatic species
Identifiers and source
- Literature Corpus work
- 7793f10a-da1d-5e05-9d8c-531b4c8cb7a8
- DOI
- 10.1101/2023.03.06.531269
