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Amphioxus: Beginning of Vertebrate and End of Invertebrate Type GnRH Receptor Lineage

5 Mar 2009

Abstract excerpt

In vertebrates, activation of the GnRH receptor is necessary to initiate the reproductive cascade. However, little is known about the characteristics of GnRH receptors before the vertebrates evolved. Recently genome sequencing was completed for amphioxus, Branchiostoma floridae. To understand the GnRH receptors (GnRHR) from this most basal chordate, which is also classified as an invertebrate, we cloned and...

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PMID: 19264870
DOI: 10.1210/en.2009-0028

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