Article

A Hybrid Pharmacovigilance Method for National-Scale Comorbidity Discovery: Association Rules with FDA-Approved PRR/Chi-square and EBGM Validation.

2025-12-24

Abstract excerpt

<title>Abstract</title> <p>Background Clinicians need scalable, statistically rigorous maps of disease–disease co-occurrence to support screening, safer prescribing, and differential diagnosis. Spontaneous-report data such as FAERS are national in scope but prone to bias, so discovery requires conservative, interpretable validation. Methods We developed a three-stage pipeline—Association Rule Mining for candida...

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Literature Corpus work: 1b9aa89a-c0ff-5fd8-a44a-f69169421886
DOI: 10.21203/rs.3.rs-8311672/v1

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