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A recombinant protein SARS-CoV-2 candidate vaccine elicits high-titer neutralizing antibodies in macaques.

2020-12-21

Abstract excerpt

Vaccines that generate robust and long-lived protective immunity against SARS-CoV-2 infection are urgently required. We assessed the potential of vaccine candidates based on the SARS-CoV-2 spike in cynomolgus macaques (M. fascicularis) by examining their ability to generate spike binding antibodies with neutralizing activity. Antigens were derived from two distinct regions of the spike S1 subunit, either the N-ter...

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Identifiers and source

Literature Corpus work
7637e6da-99f9-56a2-8624-607d457d7c32
DOI
10.1101/2020.12.20.422693
Open publication

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A recombinant protein SARS-CoV-2 candidate vaccine elicits high-titer neutralizing antibodies in macaques.DOI 10.1101/2020.12.20.422693
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