Article

SARS-CoV-2 N gene dropout and N gene Ct value shift as indicator for the presence of B.1.1.7 lineage in a widely used commercial multiplex PCR assay

2021-03-26

Abstract excerpt

<h4>Objectives</h4> Increased importance in detection and surveillance of SARS-CoV-2 has been demonstrated due to the emergence of variants of concern (VOCs). In this study we evaluated if a commercially available real-time SARS-CoV-2 PCR assay can identify B.1.1.7 lineage samples by a specific N gene dropout or Ct value shift compared to the S or RdRP gene. <h4>Methods</h4> Patients samples with confirmed B.1.1.7...

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Literature Corpus work: 75e1f9d2-0062-5a98-b83b-f368d6f1bae1
DOI: 10.1101/2021.03.23.21254171

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