Article
Specific allelic discrimination of N501Y and other SARS-CoV-2 mutations by ddPCR detects B.1.1.7 lineage in Washington State.
Journal of medical virology - 1 Oct 2021
Perchetti Garrett A, Zhu Haiying, Mills Margaret G, Shrestha Lasata, Wagner Cassia, Bakhash Shah Mohamed, Lin Michelle J, Xie Hong, Huang Meei-Li, Mathias Patrick, Bedford Trevor, Jerome Keith R, Greninger Alexander L, Roychoudhury Pavitra
Abstract excerpt
Real-time epidemiological tracking of variants of concern (VOCs) can help limit the spread of more contagious forms of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), such as those containing the N501Y mutation. Typically, genetic sequencing is required to be able to track VOCs in real-time. However, sequencing can take time and may not be accessible in all laboratories. Genotyping by RT-ddPCR...
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