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Article

Heterotaxy Is Associated with Previously Unrecognised Ciliary Defects Independent of Primary Ciliary Dyskinesia

2026-03-24

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Heterotaxy (HTX) describes abnormal left–right arrangement of the organs, often associated with complex congenital heart disease (CHD). HTX is enriched in the respiratory condition primary ciliary dyskinesia (PCD) due to defective nodal cilia. A subset of patients presents with HTX and mild respiratory phenotypes but normal respiratory cilia function. The mechanisms underlyi...

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Literature Corpus work
75c1c596-0098-5310-9d71-988269d718c1
DOI
10.64898/2026.03.17.26348660
Open publication

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