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CircRNA MFACR is Upregulated in Myocardial Infarction and Downregulates miR-125b to Promote Cardiomyocyte Apoptosis-induced by Hypoxia

2020-11-18

Abstract excerpt

<h4>Background: </h4> CircRNA MFACR promotes cardiomyocyte death, which contributes to myocardial infarction (MI). We analyzed the role of MFACR in MI. <h4>Methods: </h4>: RT-qPCR was applied to determine MFACR and miR-125b expression in plasma samples from both MI patients (n=61) and healthy controls (n=61). MFACR and miR-125b were overexpressed in AC16 cells (cardiomyocytes) to study the interactions between the...

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Literature Corpus work
75bbf46b-73ff-56ee-ada7-da092cfa5917
DOI
10.21203/rs.3.rs-106353/v1
Open publication

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CircRNA&nbsp;MFACR&nbsp;is Upregulated in Myocardial Infarction and Downregulates miR-125b&nbsp;to Promote Cardiomyocyte Apoptosis-induced by HypoxiaDOI 10.21203/rs.3.rs-106353/v1
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