Article
Structural characterization of Nonstructural protein 1 from SARS-CoV-2
2020-09-08
Abstract excerpt
Severe acute respiratory syndrome (SARS) coronavirus-2 (SARS-CoV-2) is a single-stranded, enveloped RNA virus and the etiological agent of the current COVID-19 pandemic. Efficient replication of the virus relies on the activity of nonstructural protein 1 (Nsp1), a major virulence factor shown to facilitate suppression of host gene expression through promotion of host mRNA degradation and interaction with the 40S r...
Topics
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- Animal Virus Infections Studies
- COVID-19 Clinical Research Studies
- RNA and protein synthesis mechanisms
- SARS-CoV-2 and COVID-19 Research
- vaccines and immunoinformatics approaches
- Viral gastroenteritis research and epidemiology
- Viral Infections and Immunology Research
- Viral Infections and Outbreaks Research
Identifiers and source
- Literature Corpus work
- 752db7c4-50fa-58e5-8a44-0ee166a1915d
- DOI
- 10.1101/2020.09.08.288191
