Article

Physiological comparison of three spontaneous breathing trials in COVID-19 pneumoniae. Inspiratory effort, and relationship with the different phenotypes. Risk of patient self-inflicted lung injury.

2023-04-25

Abstract excerpt

<h4>Background: </h4> High drive and high effort during spontaneous breathing can generate potential patient self-inflicted lung injury (P-SILI), due to uncontrolled high transpulmonary and transvascular pressures, with relapse of respiratory failure. P-SILI has been demonstrated in experimental studies, and supported in recent computational models. Different treatment strategies have been proposed according to th...

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Literature Corpus work: 75223b69-78c6-55f0-8d1c-d055b5b9873a
DOI: 10.21203/rs.3.rs-2814255/v1

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